专利名称：MONOCLONAL ANTIBODIES AGAINST THE ALPHA PDGF RECEPTOR AND USES
2012年高考试卷THEREOF
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发明人：LaROCHELLE, William, J.,PIERCE,
dlxJacalyn,JENSEN, Roy, A.,AARONSON, Stuart,
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A.
申请号：US1994007006
申请日：19940624
公开号：WO95/000659P1
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公开日：
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19950105
专利内容由知识产权出版社提供
abcd英语26个字母的读法摘要：Potent neutralizing monoclonal antibodies to the human α PDGF receptor (αPDGFR) and fragments thereof are described. The monoclonal antibodies specifically bind to an epitope on α PDGFR, inhibit PDGF binding with PDGF receptor, antagonize PDGF, and do not bind β PDGF receptor. A hybridoma cell line producing such a monoclonal antibody, methods of in vivo imaging of a pathological condition and methods of inhibiting the growth of a neoplasia expressing α PDGFR, which u the monoclonal antibodies are also described. In vitro assays for detecting the prence of αPDGFR and for evaluating the binding affinity of a test compound are also described.
申请人：THE UNITED STATES OF AMERICA, reprented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES手语翻译
小学生英语日记>技术英文地址：US
国籍：US
代理机构：BENT, Stephen, A.更多信息请下载全文后查看
