专利名称：7-SUBSTITUTED OXASTEROID COMPOUND 发明人：KOIZUMI, Naoyuki 8-8-3,
Higashirinkan,TAKEGAWA, Shigehiro
Confort-Musashi-Nakahara 401,,IWASHITA,因为你爱过我>gab
Shigeki Teikoku Zoki Shataku,KAWACHI,
Tomoko,INOUE, Fumiko 280-6,
Iwasaki,HONMA, Seijiro 2-4-19,
Tachibanadai,TAKAHASHI, Hiroo 4-4-10,
Yookodai,MIEDA, Manoru 516,
Kashiwagaya,UEDA, Kaoru 2-13-36,
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Sugebanba,SHIBATA, Kenyu 998-4, Oshitate 申请号：EP93921086.0
申请日：19930929
公开号：EP0663402B1
me too公开日：hurly burly
19990421中学生一对一
专利内容由知识产权出版社提供
摘要：A 7-substituted oxa- or azasteroid compound reprented by general formula (I), which has an excellent aromata-inhibiting effect and is uful for preventing or treating dias caud by estrogens, such as breast cancer, uterine cancer and prostatomegaly. This compound has an oxyge
opticalmoumstpn or nitrogen atom as the heteroatom at the position A of the ring D and the 7-position (substituent R¹) of the skeleton is substituted by -S-R² (wherein R² reprents hydrogen, lower alkyl which may be substituted by hydroxy, amino or lower alkoxycarbonyl, lower alkenyl, aralkyl, aryl which may be substituted by halogen, amino, di(lower alkyl)amino, lower alkoxy or lower alkyl,
acyl, or lower alkoxycarbonyl), - S(O)m-R³ (wherein R³ reprents lower alkyl; and m reprents 1 or 2), or aralkyl.
申请人：TEIKOKU HORMONE MFG CO LTD
地址：JP生产工艺英文
国籍：JP
代理机构：Weirt, Annekäte, Dipl.-Ing. Dr.-Ing.
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