专利名称：APTAMER FOR BONDING TO AUTOTAXIN AND INHIBITING BIOLOGICAL ACTIVITY OF
六道木属AUTOTAXIN, AND USE FOR SAME
发明人：IKEDA, Hisako，池田 寿子
申请号：JP2015/062561
finland申请日：20150424
sicca
bonduniversity公开号：WO2015/163458A1
公开日：
彩排
20151029123翻译网>凯顿儿童美语
专利内容由知识产权出版社提供龙井茶英语
专利附图：
摘要： The prent invention provides an aptamer that bonds to autotaxin, said aptamer including a nucleotide quence reprented by the formula
GWAACAGGUUUUGCU (SEQ ID NO: 42) (in the formula, W is A or U, and uracil can be thymine), and being one of the following: (a) the aptamer, wherein in the nucleotide included in the aptamer, (i) the 2' position of the ribo in each pyrimidine nucleotide is a fluorine atom, and (ii) the 2' position of the ribo in each purine nucleotide is a hydroxy group; or (b) the aptamer from (a), wherein (i) the fluorine atoms at the 2' position of the ribo in each pyrimidine nucleotide are each independently unsubstituted or substituted with an atom or a group lected from the group consisting of a hydrogen atom, a hydroxy group, and a methoxy group, and (ii) the hydroxy groups at the 2' position of the ribo in each purine nucleotide are each independently unsubstituted or substituted with an atom or a group lected from the group consisting of a hydrogen atom, a methoxy group and a fluorine atom.
we are the millers申请人：RIBOMIC INC.，株式会社リボミック
hat怎么读语音地址：〒1080071 JP,〒1080071 JP
国籍：JP,JP
代理人：TAKASHIMA, Hajime，高島 一
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