专利名称：SUBSTITUTED 9-ALKYLADENINES AND THE USE THEREOF
发明人：MINASKANIAN, Gevork,RIPPEL, Keith
一套英文申请号：EP06737850.5
申请日：20060310iunderstand
石家庄环球雅思公开号：EP1863815A1
复式记帐法
dress的复数公开日：
smr20071212
专利内容由知识产权出版社提供
摘要：The invention relates to substituted 9-alkyladenines of Formula I : or a pharmaceutically acceptable salt thereof, wherein R1-R6 are defined as t forth in the specification. The invention is also directed to the u of such compounds to inhibit adenosine A1 receptor activation in a mammal. The compounds of the prent invention are uful as diuretics, renal protectives against acute or chronic renal failure, as well as agents to improve the therapeutic outcome resulting from defibrillation or cardiopulmonary resuscitation by preventing post-resuscitation bradycardia, bradyarrythmia and cardioplegia, to restore cardiac function following a cardioplegic procedure, and to treat or prevent intermittent claudication.
申请人：Aderis Pharmaceuticals, Inc.drive
地址：85 Main Street Hopkinton, MA 01748 US
unlock>livelihood国籍：US
代理机构：Grünecker, Kinkeldey, Stockmair & Schwanhäusr Anwaltssozietät
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