专利名称:CYCLIC CARBAMATE ANALOGUES OF (+)-PILOCARPINE
发明人:HENRY RAPOPORT,PER SAUERBERG
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由衷的意思申请号:AU5330490
申请日:19900227
公开号:AU5330490A
挽回男人公开日:
语泉19900926
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张璐 翻译专利内容由知识产权出版社提供
huangtu>乔治 索罗斯金山翻译软件摘要:Pilocarpine analogues are provided having the structure where one of R1 or R2 is an alkyl, such as methyl, ethyl, propyl, butyl, and so forth, and the corresponding condary alkyl groups, an aralkyl, such as benzyl, phenylethyl, phenylpropyl, and the corresponding condary aralkyl residues, or a cycloalkyl having less than about 12 carbon atoms. R3 has at least two carbon atoms but less than about 9. The pilocarpine analogues have improved duration of biological activity with respect to pilocarpine. A particularly preferred compound is a muscarinic agonist equipotent with pilocarpine, where R2 is methyl, and R3 is ethyl.
申请人:THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
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