专利名称:A COMBINATION OF A 5-HT REUPTAKE INHIBITOR AND A h5-HT 1B ANTAGONIST
OR PARTIAL AGONIST
杀鸡吓猴发明人:BERG, Stefan,ROSS, Svante,THORBERG, Seth-Olov
申请号:EP98944375.9
申请日:19980909
公开号:EP1014985A1
opportunity公开日:
dress怎么读
原来如此 日语20000705
专利内容由知识产权出版社提供
donnie yen摘要:Carrying out the h5-HT1B antagonists of lectivity or partial agonist the prent invention relates to a kind of a kind of 5-HT reuptake inhibitors of the first component (a) of combination and cond of component (two) has formula (I), and wherein X is CH2, O; Y CONH, NHCO; R1 is H, C1-C6 alkyl, C3-C6 naphthenic ba; R2 is H, C1-C6 alkyl, C1-C6 alkoxies, halogen; R3 is (1), (2), (3), CF3; R4 and R5 stands alone as H or C1-C4 alkyl, as racemic modification, R- enantiomers or S- enantiomers, and the form of the component (a) and component (b) is in free bas, solvent or its pharmaceutically acceptable salt, and its preparation, the pharmaceutical preparation containing the compounds of this invention, the combination us and treats the disturbance of emotion such as depression and anxiety and OCD and the combined kit and comprising the combination.domesticated>burial
申请人:AstraZeneca AB
地址:151 85 Södertälje SE
国籍:SEin your mind>利润表
更多信息请下载全文后查看daegu