Single-chain coiled coil scaffold

更新时间:2023-06-21 10:17:13 阅读: 评论:0

太棒了英文专利名称:Single-chain coiled coil scaffold 发明人:Desmet, Johan,Lasters, Ignace
2012上海高考数学申请号:EP08172017.9
中招考试注意事项申请日:20081217
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japane公开号:EP2161278B1
公开日:
bole
游戏培训学院
20120523
专利内容由知识产权出版社提供
摘要:The prent invention is related to a single-chain protein scaffold of the formula HRS1-L1-HRS2-L2-HRS3, wherein HRS1, HRS2 and HRS3 are heptad repeat quences and L1 and L2 are structurally flexible linker quences, and wherein HRS1, HRS2 and HRS3 form a thermodynamically stable triple-stranded, parallel, alpha-helical coiled coil structure in solution. The invention is further related to amino acid quence variants, variants with optimized linkers and helix-capping amino acid residues, variants displaying a binding groove and variants displaying binding to a target molecule.感激不尽
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申请人:COMPLIX N V
地址:BE
bear国籍:BE
代理机构:Taormino, Joph Paul
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