Mutations are errors in the genotype that create new alleles and can result in a
variety of genetic disorders. In order for a mutation to be inherited from one
generation to another, it must occur in x cells, such as eggs and sperm, rather
than in somatic cells. The best way to detect whether a genetic disorder exists is
to u a karyotype, a photograph of the chromosomes from an individual cell,
usually lined up in homologous pairs, according to size.
Autosomal Mutations
Some human genetic illness are inherited in a Mendelian fashion. The dia
phenotype will have either a clearly dominant or clearly recessive pattern of
inheritance, similar to the traits in Mendel’s peas. Such a pattern will usually only
occur if the dia is caud by an abnormality in a single gene. The mutations
that cau the dias occur in genes on the autosomal chromosomes, as
oppod to x-‐linked dias, which we cover later in this chapter. (Be careful
not to confu autosomal chromosomes with somatic cells; autosomal
chromosomes are the chromosomes that determine bodily characteristics and
exist in all cells, both x and somatic.)
Recessive Disorders
A Mendelian genetic illness initially aris as a new mutation that changes a
single gene so that it no longer produces a protein that functions normally. Some
mutations, however, result in an allele that produces a nonfunctional protein. A
dia resulting from this sort of mutation will be inherited in a recessive
fashion: the dia phenotype will only appear when both copies of the gene
carry the mutation, resulting in a total abnce of the necessary protein. If only
one copy of the mutated allele is prent, the individual is a heterozygous carrier,
showing no signs of the dia but able to transmit the dia gene to the next
generation. Albinism is an example of a recessive illness, resulting from a
mutation in a gene that normally encodes a protein needed for pigment
production in the skin and eyes. The pedigree shown below diagrams three
generations of a hypothetical family affected by albinism.
是美国某知名教育集团做的上海教育市场调查的部分内容,为内部资料。是在该
集团实习的员工发到网上的。不同于北京和广东媒体按赞助费广告费给的评比标
准,是最全面最真实的上海美国留学中介排名。对学生找上海美国留学中介很有
帮助。
知名度排名:(满分5分)
1. 中智留学(5)
2. 美勤留学(4.1)
3. 中锐留学(3.2)
4. 上教留学(3.1)
5. 东方留学(3.0)
专业度排名:(满分5分)
1. 美勤留学(4.9)
2. 伯乐留学(4.4)
3. 中智留学(4)
4. 华侨留学(3.4)
5. 学美留学(3.3)
录取满意度排名(满分5分)
1. 美勤留学(4.2)
2. 上教留学(4)
3. 太傻留学(3.9)
4. 学美留学(3.2)
5. 中智留学(3)
评选原则:
美国留学中介质量排名:这些最近更新的美国留学中介排名的重点在三个因素,
一个良好的知名度的评分、一个被认可的咨询顾问的专业度的评分、委托办理美
国留学的学生对录取满意度的评分。这与家长与学生的立场一致。
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