thalland

期刊名称：Autoimmunity

作者：Thall,Aron,Etienne-decerf,Jacqueline,Winand,RogerJ.,Galili,Uri

年份：1991年

期号：第2期

关键词：α-Galactosylepitope;thyroid;anti-Galantibody;autoimmunity

摘要：Asmuchas1%ofcirculatingIgGinman(thenaturalanti-Galantibody)is

directedagainstthe±-galactosylepitope,withthestructureGal±l3Gall4GlcNAc-R.

The±-galactosylepitopeisabundantlyexpresdoncellsofnonprimatemammals,

prosimians,ressionisdiminishedinOldWorld

monkeys,apes,eenpreviouslysuggestedthatinteraction

betweenanti-Galandaberrantlyexpresd±-galactosylepitopesonthyroidcells

ythis

possibility,±-galactosylepitopeexpressiononthyroidcellmembranesofnormal

individualsandpatientswithGraves''diawasassdbyansitive

radioimmunoassay.±-Galactosylepitopeswerefoundbothonnormalanddiad

stheconcentrationofthe...

内容由中国教育图书进出口有限公司引进

Theα-GalactosylEpitopeonHumanNormaland

AutoimmuneThyroidCells