国外化学经典教材系列

内容简介

《质谱(原著第2版)(英文版)》作为一部成功的教科书，其全新修订的第2版在内容上得以充分的扩展，以其详尽和准确的叙述，精美的插图和照片为读者津津乐道。?新增串级质谱法，涵盖了仪器设备、离子激活方法（CID，ECD，ETD，IRMPD）及其应用？新增敞开式质谱（DART，DESI等），新增无机质谱，包含元素形态分析和成像，?新增了所有章节的学习目标，新增先进仪器介绍，诸如orbitraps、线性离子阱、串级TOFs、FT-ICR，以及各种联用仪器。JurgenH.Gross对书中的概念、方法和技术做出了深入的阐述。指导学生和专业人员从新手逐步成长为质谱应用的行家里手。JurgenH.Gross首先介绍了气相离子化学原理、同位素组成和精确质量，然后是各种质量分析器和离子化方法的设计，最后是质谱图的解析和联用技术。可以说《质谱(原著第2版)(英文版)》是实用信息和基于丰富文献的理论知识的完美结合。

目录

Table of Contents

1 Introduction

Learning Objectives

1.1 Aims and Scope

1.1.1 Filling the Black Box

1.2 What Is Mass Spectrometry？

1.2.1 Mass Spectrometry

1.2.2 Mass Spectrometer

1.2.3 Mass Scale

1.2.4 Mass Spectrum

1.3 Ion Chromatograms

1.4 Performance of Mass Spectrometers

1.4.1 Sensitivity

1.4.2 Detection Limit

1.4.3 Signal-to-Noi Ratio

1.5 Terminology - General Aspects

1.5.1 Basic Terminology in Describing Mass Spectra

1.6 Units, Physical Quantities, and Physical Constants

References

2 Principles of Ionization and Ion Dissociation

Learning Objectives

2.1 Gas Pha Ionization by Energetic Electrons

2.1.1 Formation of Ions

2.1.2 Process Accompanying Electron Ionization

2.1.3 Ions Generated by Penning Ionization

2.1.4 Ionization Energy

2.1.5 Ionization Energy and Charge-Localization

2.2 Vertical Transitions

2.3 Ionization Efficiency and Ionization Cross Section

2.4 Internal Energy and the Further Fate of Ions

2.4.1 Degrees of Freedom

2.4.2 Appearance Energy

2.4.3 Bond Dissociation Energies and Heats of Formation

2.4.4 Randomization of Energy

2.5 Quasi-Equilibrium Theory

2.5.1 QET's Basic Premis

2.5.2 Basic QET

2.5.3 Rate Constants and Their Meaning

2.5.4 k（E） Functions - Typical Examples

2.5.5 Reacting Ions Described by k（E）Functions

2.5.6 Direct Cleavages and Rearrangement Fragmentations

2.6 Time Scale of Events

2.6.1 Stable, Metastable, and Unstable Ions

2.6.2 Time Scale of Ion Storage Devices

2.7 Internal Energy - Practical Implications

2.8 Rever Reactions and Kinetic Energy Relea

2.8.1 Activation Energy of the Rever Reaction

2.8.2 Kinetic Energy Relea

2.8.3 Energy Partitioning

2.9 Isotope Effects

2.9.1 Primary Kinetic Isotope Effects

2.9.2 Measurement of Isotope Effects

2.9.3 Secondary Kinetic Isotope Effects

2.10 Determination of Ionization Energies

2.10.1 Conventional Determination of Ionization Energies

2.10.2 Improved IE Accuracy from Data Post-Processing

2.10.3 IE Accuracy - Experimental Improvements

2.10.4 Photoionization Process

2.11 Determining the Appearance Energies

2.11.1 Kinetic Shift

2.11.2 Breakdown Graphs

2.12 Gas Pha Basicity and Proton Affinity

References

3 Isotopic Composition and Accurate Mass

Learning Objectives

3.1 Isotopic Classification of the Elements

3.1.1 Monoisotopic Elements

3.1.2 Di-isotopic Elements .

3.1.3 Polyisotopic Elements

3.1.4 Reprentation of Isotopic Abundances

3.1.5 Calculation of Atomic, Molecular, and Ionic Mass

3.1.6 Natural Variations in Relative Atomic Mass

3.2 Calculation of Isotopic Distributions

3.2.1 Carbon: An X+I Element

……

4 Instrumentation

5 Practical Aspects of Electron Ionization...

6 Fragmentation of Organic Ions and Interpretation of E1 Mass Spectra

7 Chemical Ionization

8 Field Ionization and Field Desorption

9 Tandem Mass Spectrometry

10 Fast Atom Bombardment

11 Matrix-Assisted Lar Desorption/Ionization

12 Electrospray Ionization

13 Ambient Mass Spectrometry

14 Hyphenated Methods

15 Inorganic Mass Spectrometry

Appendix

Subject Index